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European-American COPD 14:33 Tuesday, June 18, 2002 4
SNP = CD14.1283
Allele Frequency
Frequency|
Percent |A |G | Total
---------+--------+--------+
Case | 292 | 2 | 294
| 68.22 | 0.47 | 68.69
---------+--------+--------+
Control | 133 | 1 | 134
| 31.07 | 0.23 | 31.31
---------+--------+--------+
Total 425 3 428
99.30 0.70 100.00
Frequency Missing = 22
Statistics for Table of Allele Frequency
Statistic DF Value Prob
------------------------------------------------------
Chi-Square 1 0.0058 0.9395
Likelihood Ratio Chi-Square 1 0.0057 0.9398
Continuity Adj. Chi-Square 1 0.0000 1.0000
Mantel-Haenszel Chi-Square 1 0.0057 0.9396
Phi Coefficient 0.0037
Contingency Coefficient 0.0037
Cramer's V 0.0037
WARNING: 50% of the cells have expected counts less
than 5. Chi-Square may not be a valid test.
Fisher's Exact Test
----------------------------------
Cell (1,1) Frequency (F) 292
Left-sided Pr <= F 0.7679
Right-sided Pr >= F 0.6769
Table Probability (P) 0.4448
Two-sided Pr <= P 1.0000
Estimates of the Relative Risk (Row1/Row2)
Type of Study Value 95% Confidence Limits
-----------------------------------------------------------------
Case-Control (Odds Ratio) 1.0977 0.0987 12.2124
Cohort (Col1 Risk) 1.0007 0.9833 1.0183
Cohort (Col2 Risk) 0.9116 0.0834 9.9658
Effective Sample Size = 428
Frequency Missing = 22
European-American COPD 14:33 Tuesday, June 18, 2002 5
SNP = CD14.1283
Allele Frequency
Frequency|
Percent |AA |GA | Total
---------+--------+--------+
Case | 145 | 2 | 147
| 67.76 | 0.93 | 68.69
---------+--------+--------+
Control | 66 | 1 | 67
| 30.84 | 0.47 | 31.31
---------+--------+--------+
Total 211 3 214
98.60 1.40 100.00
Frequency Missing = 11
Statistics for Table of Allele Frequency
Statistic DF Value Prob
------------------------------------------------------
Chi-Square 1 0.0058 0.9393
Likelihood Ratio Chi-Square 1 0.0057 0.9396
Continuity Adj. Chi-Square 1 0.0000 1.0000
Mantel-Haenszel Chi-Square 1 0.0058 0.9394
Phi Coefficient 0.0052
Contingency Coefficient 0.0052
Cramer's V 0.0052
WARNING: 50% of the cells have expected counts less than 5.
(Asymptotic) Chi-Square may not be a valid test.
Pearson Chi-Square Test
----------------------------------
Chi-Square 0.0058
DF 1
Asymptotic Pr > ChiSq 0.9393
Exact Pr >= ChiSq 1.0000
Fisher's Exact Test
----------------------------------
Cell (1,1) Frequency (F) 145
Left-sided Pr <= F 0.7685
Right-sided Pr >= F 0.6780
Table Probability (P) 0.4464
Two-sided Pr <= P 1.0000
European-American COPD 14:33 Tuesday, June 18, 2002 6
SNP = CD14.1283
Statistics for Table of Allele Frequency
Estimates of the Relative Risk (Row1/Row2)
Type of Study Value 95% Confidence Limits
-----------------------------------------------------------------
Case-Control (Odds Ratio) 1.0985 0.0979 12.3291
Cohort (Col1 Risk) 1.0013 0.9668 1.0371
Cohort (Col2 Risk) 0.9116 0.0841 9.8790
Odds Ratio (Case-Control Study)
-----------------------------------
Odds Ratio 1.0985
Asymptotic Conf Limits
95% Lower Conf Limit 0.0979
95% Upper Conf Limit 12.3291
Exact Conf Limits
95% Lower Conf Limit 0.0183
95% Upper Conf Limit 21.4377
Effective Sample Size = 214
Frequency Missing = 11
European-American COPD 14:33 Tuesday, June 18, 2002 7
SNP = CD14.6080
Allele Frequency
Frequency|
Percent |A |G | Total
---------+--------+--------+
Case | 157 | 127 | 284
| 38.29 | 30.98 | 69.27
---------+--------+--------+
Control | 68 | 58 | 126
| 16.59 | 14.15 | 30.73
---------+--------+--------+
Total 225 185 410
54.88 45.12 100.00
Frequency Missing = 40
Statistics for Table of Allele Frequency
Statistic DF Value Prob
------------------------------------------------------
Chi-Square 1 0.0608 0.8052
Likelihood Ratio Chi-Square 1 0.0608 0.8053
Continuity Adj. Chi-Square 1 0.0193 0.8894
Mantel-Haenszel Chi-Square 1 0.0607 0.8055
Phi Coefficient 0.0122
Contingency Coefficient 0.0122
Cramer's V 0.0122
Fisher's Exact Test
----------------------------------
Cell (1,1) Frequency (F) 157
Left-sided Pr <= F 0.6388
Right-sided Pr >= F 0.4442
Table Probability (P) 0.0830
Two-sided Pr <= P 0.8302
Estimates of the Relative Risk (Row1/Row2)
Type of Study Value 95% Confidence Limits
-----------------------------------------------------------------
Case-Control (Odds Ratio) 1.0544 0.6919 1.6068
Cohort (Col1 Risk) 1.0243 0.8452 1.2414
Cohort (Col2 Risk) 0.9715 0.7726 1.2215
Effective Sample Size = 410
Frequency Missing = 40
European-American COPD 14:33 Tuesday, June 18, 2002 8
SNP = CD14.6080
Allele Frequency
Frequency|
Percent |AA |GA |GG | Total
---------+--------+--------+--------+
Case | 47 | 63 | 32 | 142
| 22.93 | 30.73 | 15.61 | 69.27
---------+--------+--------+--------+
Control | 15 | 38 | 10 | 63
| 7.32 | 18.54 | 4.88 | 30.73
---------+--------+--------+--------+
Total 62 101 42 205
30.24 49.27 20.49 100.00
Frequency Missing = 20
Statistics for Table of Allele Frequency
Statistic DF Value Prob
------------------------------------------------------
Chi-Square 2 4.4441 0.1084
Likelihood Ratio Chi-Square 2 4.4667 0.1072
Mantel-Haenszel Chi-Square 1 0.0602 0.8062
Phi Coefficient 0.1472
Contingency Coefficient 0.1457
Cramer's V 0.1472
Pearson Chi-Square Test
----------------------------------
Chi-Square 4.4441
DF 2
Asymptotic Pr > ChiSq 0.1084
Exact Pr >= ChiSq 0.1101
Effective Sample Size = 205
Frequency Missing = 20
European-American COPD 14:33 Tuesday, June 18, 2002 9
SNP = CD14.7066
Allele Frequency
Frequency|
Percent |C |T | Total
---------+--------+--------+
Case | 154 | 130 | 284
| 37.75 | 31.86 | 69.61
---------+--------+--------+
Control | 66 | 58 | 124
| 16.18 | 14.22 | 30.39
---------+--------+--------+
Total 220 188 408
53.92 46.08 100.00
Frequency Missing = 42
Statistics for Table of Allele Frequency
Statistic DF Value Prob
------------------------------------------------------
Chi-Square 1 0.0347 0.8522
Likelihood Ratio Chi-Square 1 0.0347 0.8522
Continuity Adj. Chi-Square 1 0.0061 0.9376
Mantel-Haenszel Chi-Square 1 0.0346 0.8524
Phi Coefficient 0.0092
Contingency Coefficient 0.0092
Cramer's V 0.0092
Fisher's Exact Test
----------------------------------
Cell (1,1) Frequency (F) 154
Left-sided Pr <= F 0.6161
Right-sided Pr >= F 0.4684
Table Probability (P) 0.0844
Two-sided Pr <= P 0.9141
Estimates of the Relative Risk (Row1/Row2)
Type of Study Value 95% Confidence Limits
-----------------------------------------------------------------
Case-Control (Odds Ratio) 1.0410 0.6820 1.5892
Cohort (Col1 Risk) 1.0188 0.8370 1.2401
Cohort (Col2 Risk) 0.9786 0.7803 1.2273
Effective Sample Size = 408
Frequency Missing = 42
European-American COPD 14:33 Tuesday, June 18, 2002 10
SNP = CD14.7066
Allele Frequency
Frequency|
Percent |CC |CT |TT | Total
---------+--------+--------+--------+
Case | 45 | 64 | 33 | 142
| 22.06 | 31.37 | 16.18 | 69.61
---------+--------+--------+--------+
Control | 13 | 40 | 9 | 62
| 6.37 | 19.61 | 4.41 | 30.39
---------+--------+--------+--------+
Total 58 104 42 204
28.43 50.98 20.59 100.00
Frequency Missing = 21
Statistics for Table of Allele Frequency
Statistic DF Value Prob
------------------------------------------------------
Chi-Square 2 6.5413 0.0380
Likelihood Ratio Chi-Square 2 6.6197 0.0365
Mantel-Haenszel Chi-Square 1 0.0355 0.8506
Phi Coefficient 0.1791
Contingency Coefficient 0.1763
Cramer's V 0.1791
Pearson Chi-Square Test
----------------------------------
Chi-Square 6.5413
DF 2
Asymptotic Pr > ChiSq 0.0380
Exact Pr >= ChiSq 0.0395
Effective Sample Size = 204
Frequency Missing = 21
European-American Asthma 14:33 Tuesday, June 18, 2002 11
SNP = CD14.1283
Allele Frequency
Frequency|
Percent |A |G | Total
---------+--------+--------+
Case | 292 | 2 | 294
| 64.60 | 0.44 | 65.04
---------+--------+--------+
Control | 158 | 0 | 158
| 34.96 | 0.00 | 34.96
---------+--------+--------+
Total 450 2 452
99.56 0.44 100.00
Frequency Missing = 36
Statistics for Table of Allele Frequency
Statistic DF Value Prob
------------------------------------------------------
Chi-Square 1 1.0796 0.2988
Likelihood Ratio Chi-Square 1 1.7252 0.1890
Continuity Adj. Chi-Square 1 0.0876 0.7673
Mantel-Haenszel Chi-Square 1 1.0772 0.2993
Phi Coefficient -0.0489
Contingency Coefficient 0.0488
Cramer's V -0.0489
WARNING: 50% of the cells have expected counts less
than 5. Chi-Square may not be a valid test.
Fisher's Exact Test
----------------------------------
Cell (1,1) Frequency (F) 292
Left-sided Pr <= F 0.4226
Right-sided Pr >= F 1.0000
Table Probability (P) 1.4226
Two-sided Pr <= P 0.5443
Estimates of the Relative Risk (Row1/Row2)
Type of Study Value 95% Confidence Limits
-----------------------------------------------------------------
Cohort (Col1 Risk) 0.9932 0.9838 1.0026
One or more risk estimates not computed --- zero cell.
Effective Sample Size = 452
Frequency Missing = 36
European-American Asthma 14:33 Tuesday, June 18, 2002 12
SNP = CD14.1283
Allele Frequency
Frequency|
Percent |AA |GA | Total
---------+--------+--------+
Case | 145 | 2 | 147
| 64.16 | 0.88 | 65.04
---------+--------+--------+
Control | 79 | 0 | 79
| 34.96 | 0.00 | 34.96
---------+--------+--------+
Total 224 2 226
99.12 0.88 100.00
Frequency Missing = 18
Statistics for Table of Allele Frequency
Statistic DF Value Prob
------------------------------------------------------
Chi-Square 1 1.0844 0.2977
Likelihood Ratio Chi-Square 1 1.7300 0.1884
Continuity Adj. Chi-Square 1 0.0880 0.7668
Mantel-Haenszel Chi-Square 1 1.0796 0.2988
Phi Coefficient -0.0693
Contingency Coefficient 0.0691
Cramer's V -0.0693
WARNING: 50% of the cells have expected counts less than 5.
(Asymptotic) Chi-Square may not be a valid test.
Pearson Chi-Square Test
----------------------------------
Chi-Square 1.0844
DF 1
Asymptotic Pr > ChiSq 0.2977
Exact Pr >= ChiSq 0.5432
Fisher's Exact Test
----------------------------------
Cell (1,1) Frequency (F) 145
Left-sided Pr <= F 0.4221
Right-sided Pr >= F 1.0000
Table Probability (P) 1.4221
Two-sided Pr <= P 0.5432
Estimates of the Relative Risk (Row1/Row2)
Type of Study Value 95% Confidence Limits
-----------------------------------------------------------------
Cohort (Col1 Risk) 0.9864 0.9678 1.0053
One or more risk estimates not computed --- zero cell.
Effective Sample Size = 226
Frequency Missing = 18
European-American Asthma 14:33 Tuesday, June 18, 2002 13
SNP = CD14.6080
Allele Frequency
Frequency|
Percent |A |G | Total
---------+--------+--------+
Case | 168 | 124 | 292
| 37.67 | 27.80 | 65.47
---------+--------+--------+
Control | 85 | 69 | 154
| 19.06 | 15.47 | 34.53
---------+--------+--------+
Total 253 193 446
56.73 43.27 100.00
Frequency Missing = 42
Statistics for Table of Allele Frequency
Statistic DF Value Prob
------------------------------------------------------
Chi-Square 1 0.2248 0.6354
Likelihood Ratio Chi-Square 1 0.2245 0.6356
Continuity Adj. Chi-Square 1 0.1396 0.7087
Mantel-Haenszel Chi-Square 1 0.2243 0.6358
Phi Coefficient 0.0225
Contingency Coefficient 0.0224
Cramer's V 0.0225
Fisher's Exact Test
----------------------------------
Cell (1,1) Frequency (F) 168
Left-sided Pr <= F 0.7175
Right-sided Pr >= F 0.3539
Table Probability (P) 0.0714
Two-sided Pr <= P 0.6878
Estimates of the Relative Risk (Row1/Row2)
Type of Study Value 95% Confidence Limits
-----------------------------------------------------------------
Case-Control (Odds Ratio) 1.0998 0.7422 1.6298
Cohort (Col1 Risk) 1.0424 0.8767 1.2394
Cohort (Col2 Risk) 0.9478 0.7604 1.1814
Effective Sample Size = 446
Frequency Missing = 42
European-American Asthma 14:33 Tuesday, June 18, 2002 14
SNP = CD14.6080
Allele Frequency
Frequency|
Percent |AA |GA |GG | Total
---------+--------+--------+--------+
Case | 49 | 70 | 27 | 146
| 21.97 | 31.39 | 12.11 | 65.47
---------+--------+--------+--------+
Control | 24 | 37 | 16 | 77
| 10.76 | 16.59 | 7.17 | 34.53
---------+--------+--------+--------+
Total 73 107 43 223
32.74 47.98 19.28 100.00
Frequency Missing = 21
Statistics for Table of Allele Frequency
Statistic DF Value Prob
------------------------------------------------------
Chi-Square 2 0.2249 0.8936
Likelihood Ratio Chi-Square 2 0.2240 0.8940
Mantel-Haenszel Chi-Square 1 0.2188 0.6399
Phi Coefficient 0.0318
Contingency Coefficient 0.0317
Cramer's V 0.0318
Pearson Chi-Square Test
----------------------------------
Chi-Square 0.2249
DF 2
Asymptotic Pr > ChiSq 0.8936
Exact Pr >= ChiSq 0.8978
Effective Sample Size = 223
Frequency Missing = 21
European-American Asthma 14:33 Tuesday, June 18, 2002 15
SNP = CD14.7066
Allele Frequency
Frequency|
Percent |C |T | Total
---------+--------+--------+
Case | 164 | 132 | 296
| 36.61 | 29.46 | 66.07
---------+--------+--------+
Control | 83 | 69 | 152
| 18.53 | 15.40 | 33.93
---------+--------+--------+
Total 247 201 448
55.13 44.87 100.00
Frequency Missing = 40
Statistics for Table of Allele Frequency
Statistic DF Value Prob
------------------------------------------------------
Chi-Square 1 0.0260 0.8719
Likelihood Ratio Chi-Square 1 0.0260 0.8719
Continuity Adj. Chi-Square 1 0.0037 0.9514
Mantel-Haenszel Chi-Square 1 0.0259 0.8721
Phi Coefficient 0.0076
Contingency Coefficient 0.0076
Cramer's V 0.0076
Fisher's Exact Test
----------------------------------
Cell (1,1) Frequency (F) 164
Left-sided Pr <= F 0.6035
Right-sided Pr >= F 0.4753
Table Probability (P) 0.0788
Two-sided Pr <= P 0.9202
Estimates of the Relative Risk (Row1/Row2)
Type of Study Value 95% Confidence Limits
-----------------------------------------------------------------
Case-Control (Odds Ratio) 1.0329 0.6972 1.5302
Cohort (Col1 Risk) 1.0147 0.8498 1.2116
Cohort (Col2 Risk) 0.9824 0.7918 1.2189
Effective Sample Size = 448
Frequency Missing = 40
European-American Asthma 14:33 Tuesday, June 18, 2002 16
SNP = CD14.7066
Allele Frequency
Frequency|
Percent |CC |CT |TT | Total
---------+--------+--------+--------+
Case | 47 | 70 | 31 | 148
| 20.98 | 31.25 | 13.84 | 66.07
---------+--------+--------+--------+
Control | 23 | 37 | 16 | 76
| 10.27 | 16.52 | 7.14 | 33.93
---------+--------+--------+--------+
Total 70 107 47 224
31.25 47.77 20.98 100.00
Frequency Missing = 20
Statistics for Table of Allele Frequency
Statistic DF Value Prob
------------------------------------------------------
Chi-Square 2 0.0563 0.9722
Likelihood Ratio Chi-Square 2 0.0565 0.9722
Mantel-Haenszel Chi-Square 1 0.0250 0.8743
Phi Coefficient 0.0159
Contingency Coefficient 0.0159
Cramer's V 0.0159
Pearson Chi-Square Test
----------------------------------
Chi-Square 0.0563
DF 2
Asymptotic Pr > ChiSq 0.9722
Exact Pr >= ChiSq 0.9824
Effective Sample Size = 224
Frequency Missing = 20
European-American MI 14:33 Tuesday, June 18, 2002 17
SNP = CD14.1283
Allele Frequency
Frequency|
Percent |A |G | Total
---------+--------+--------+
Case | 253 | 1 | 254
| 65.54 | 0.26 | 65.80
---------+--------+--------+
Control | 131 | 1 | 132
| 33.94 | 0.26 | 34.20
---------+--------+--------+
Total 384 2 386
99.48 0.52 100.00
Frequency Missing = 34
Statistics for Table of Allele Frequency
Statistic DF Value Prob
------------------------------------------------------
Chi-Square 1 0.2231 0.6367
Likelihood Ratio Chi-Square 1 0.2116 0.6455
Continuity Adj. Chi-Square 1 0.0000 1.0000
Mantel-Haenszel Chi-Square 1 0.2225 0.6371
Phi Coefficient 0.0240
Contingency Coefficient 0.0240
Cramer's V 0.0240
WARNING: 50% of the cells have expected counts less
than 5. Chi-Square may not be a valid test.
Fisher's Exact Test
----------------------------------
Cell (1,1) Frequency (F) 253
Left-sided Pr <= F 0.8836
Right-sided Pr >= F 0.5676
Table Probability (P) 0.4512
Two-sided Pr <= P 1.0000
Estimates of the Relative Risk (Row1/Row2)
Type of Study Value 95% Confidence Limits
-----------------------------------------------------------------
Case-Control (Odds Ratio) 1.9313 0.1198 31.1252
Cohort (Col1 Risk) 1.0037 0.9870 1.0207
Cohort (Col2 Risk) 0.5197 0.0328 8.2424
Effective Sample Size = 386
Frequency Missing = 34
European-American MI 14:33 Tuesday, June 18, 2002 18
SNP = CD14.1283
Allele Frequency
Frequency|
Percent |AA |GA | Total
---------+--------+--------+
Case | 126 | 1 | 127
| 65.28 | 0.52 | 65.80
---------+--------+--------+
Control | 65 | 1 | 66
| 33.68 | 0.52 | 34.20
---------+--------+--------+
Total 191 2 193
98.96 1.04 100.00
Frequency Missing = 17
Statistics for Table of Allele Frequency
Statistic DF Value Prob
------------------------------------------------------
Chi-Square 1 0.2243 0.6358
Likelihood Ratio Chi-Square 1 0.2128 0.6446
Continuity Adj. Chi-Square 1 0.0000 1.0000
Mantel-Haenszel Chi-Square 1 0.2231 0.6367
Phi Coefficient 0.0341
Contingency Coefficient 0.0341
Cramer's V 0.0341
WARNING: 50% of the cells have expected counts less than 5.
(Asymptotic) Chi-Square may not be a valid test.
Pearson Chi-Square Test
----------------------------------
Chi-Square 0.2243
DF 1
Asymptotic Pr > ChiSq 0.6358
Exact Pr >= ChiSq 1.0000
Fisher's Exact Test
----------------------------------
Cell (1,1) Frequency (F) 126
Left-sided Pr <= F 0.8842
Right-sided Pr >= F 0.5682
Table Probability (P) 0.4524
Two-sided Pr <= P 1.0000
European-American MI 14:33 Tuesday, June 18, 2002 19
SNP = CD14.1283
Statistics for Table of Allele Frequency
Estimates of the Relative Risk (Row1/Row2)
Type of Study Value 95% Confidence Limits
-----------------------------------------------------------------
Case-Control (Odds Ratio) 1.9385 0.1193 31.4946
Cohort (Col1 Risk) 1.0074 0.9740 1.0419
Cohort (Col2 Risk) 0.5197 0.0330 8.1766
Odds Ratio (Case-Control Study)
-----------------------------------
Odds Ratio 1.9385
Asymptotic Conf Limits
95% Lower Conf Limit 0.1193
95% Upper Conf Limit 31.4946
Exact Conf Limits
95% Lower Conf Limit 0.0243
95% Upper Conf Limit 153.3486
Effective Sample Size = 193
Frequency Missing = 17
European-American MI 14:33 Tuesday, June 18, 2002 20
SNP = CD14.6080
Allele Frequency
Frequency|
Percent |A |G | Total
---------+--------+--------+
Case | 125 | 119 | 244
| 34.72 | 33.06 | 67.78
---------+--------+--------+
Control | 58 | 58 | 116
| 16.11 | 16.11 | 32.22
---------+--------+--------+
Total 183 177 360
50.83 49.17 100.00
Frequency Missing = 60
Statistics for Table of Allele Frequency
Statistic DF Value Prob
------------------------------------------------------
Chi-Square 1 0.0476 0.8274
Likelihood Ratio Chi-Square 1 0.0476 0.8274
Continuity Adj. Chi-Square 1 0.0111 0.9162
Mantel-Haenszel Chi-Square 1 0.0474 0.8276
Phi Coefficient 0.0115
Contingency Coefficient 0.0115
Cramer's V 0.0115
Fisher's Exact Test
----------------------------------
Cell (1,1) Frequency (F) 125
Left-sided Pr <= F 0.6297
Right-sided Pr >= F 0.4580
Table Probability (P) 0.0877
Two-sided Pr <= P 0.9102
Estimates of the Relative Risk (Row1/Row2)
Type of Study Value 95% Confidence Limits
-----------------------------------------------------------------
Case-Control (Odds Ratio) 1.0504 0.6751 1.6345
Cohort (Col1 Risk) 1.0246 0.8228 1.2759
Cohort (Col2 Risk) 0.9754 0.7806 1.2189
Effective Sample Size = 360
Frequency Missing = 60
WARNING: 14% of the data are missing.
European-American MI 14:33 Tuesday, June 18, 2002 21
SNP = CD14.6080
Allele Frequency
Frequency|
Percent |AA |GA |GG | Total
---------+--------+--------+--------+
Case | 32 | 61 | 29 | 122
| 17.78 | 33.89 | 16.11 | 67.78
---------+--------+--------+--------+
Control | 12 | 34 | 12 | 58
| 6.67 | 18.89 | 6.67 | 32.22
---------+--------+--------+--------+
Total 44 95 41 180
24.44 52.78 22.78 100.00
Frequency Missing = 30
Statistics for Table of Allele Frequency
Statistic DF Value Prob
------------------------------------------------------
Chi-Square 2 1.2109 0.5458
Likelihood Ratio Chi-Square 2 1.2186 0.5437
Mantel-Haenszel Chi-Square 1 0.0501 0.8229
Phi Coefficient 0.0820
Contingency Coefficient 0.0817
Cramer's V 0.0820
Pearson Chi-Square Test
----------------------------------
Chi-Square 1.2109
DF 2
Asymptotic Pr > ChiSq 0.5458
Exact Pr >= ChiSq 0.5591
Effective Sample Size = 180
Frequency Missing = 30
WARNING: 14% of the data are missing.
European-American MI 14:33 Tuesday, June 18, 2002 22
SNP = CD14.7066
Allele Frequency
Frequency|
Percent |C |T | Total
---------+--------+--------+
Case | 130 | 126 | 256
| 34.57 | 33.51 | 68.09
---------+--------+--------+
Control | 61 | 59 | 120
| 16.22 | 15.69 | 31.91
---------+--------+--------+
Total 191 185 376
50.80 49.20 100.00
Frequency Missing = 44
Statistics for Table of Allele Frequency
Statistic DF Value Prob
------------------------------------------------------
Chi-Square 1 0.0001 0.9925
Likelihood Ratio Chi-Square 1 0.0001 0.9925
Continuity Adj. Chi-Square 1 0.0000 1.0000
Mantel-Haenszel Chi-Square 1 0.0001 0.9925
Phi Coefficient -0.0005
Contingency Coefficient 0.0005
Cramer's V -0.0005
Fisher's Exact Test
----------------------------------
Cell (1,1) Frequency (F) 130
Left-sided Pr <= F 0.5404
Right-sided Pr >= F 0.5477
Table Probability (P) 0.0881
Two-sided Pr <= P 1.0000
Estimates of the Relative Risk (Row1/Row2)
Type of Study Value 95% Confidence Limits
-----------------------------------------------------------------
Case-Control (Odds Ratio) 0.9979 0.6467 1.5398
Cohort (Col1 Risk) 0.9990 0.8071 1.2365
Cohort (Col2 Risk) 1.0011 0.8030 1.2479
Effective Sample Size = 376
Frequency Missing = 44
WARNING: 10% of the data are missing.
European-American MI 14:33 Tuesday, June 18, 2002 23
SNP = CD14.7066
Allele Frequency
Frequency|
Percent |CC |CT |TT | Total
---------+--------+--------+--------+
Case | 30 | 70 | 28 | 128
| 15.96 | 37.23 | 14.89 | 68.09
---------+--------+--------+--------+
Control | 13 | 35 | 12 | 60
| 6.91 | 18.62 | 6.38 | 31.91
---------+--------+--------+--------+
Total 43 105 40 188
22.87 55.85 21.28 100.00
Frequency Missing = 22
Statistics for Table of Allele Frequency
Statistic DF Value Prob
------------------------------------------------------
Chi-Square 2 0.2207 0.8955
Likelihood Ratio Chi-Square 2 0.2213 0.8953
Mantel-Haenszel Chi-Square 1 0.0001 0.9920
Phi Coefficient 0.0343
Contingency Coefficient 0.0342
Cramer's V 0.0343
Pearson Chi-Square Test
----------------------------------
Chi-Square 0.2207
DF 2
Asymptotic Pr > ChiSq 0.8955
Exact Pr >= ChiSq 0.9322
Effective Sample Size = 188
Frequency Missing = 22
WARNING: 10% of the data are missing.
European-American DVT 14:33 Tuesday, June 18, 2002 24
SNP = CD14.1283
Allele Frequency
Frequency|
Percent |A |G | Total
---------+--------+--------+
Case | 129 | 3 | 132
| 49.62 | 1.15 | 50.77
---------+--------+--------+
Control | 128 | 0 | 128
| 49.23 | 0.00 | 49.23
---------+--------+--------+
Total 257 3 260
98.85 1.15 100.00
Frequency Missing = 20
Statistics for Table of Allele Frequency
Statistic DF Value Prob
------------------------------------------------------
Chi-Square 1 2.9430 0.0862
Likelihood Ratio Chi-Square 1 4.1012 0.0429
Continuity Adj. Chi-Square 1 1.2877 0.2565
Mantel-Haenszel Chi-Square 1 2.9317 0.0869
Phi Coefficient -0.1064
Contingency Coefficient 0.1058
Cramer's V -0.1064
WARNING: 50% of the cells have expected counts less
than 5. Chi-Square may not be a valid test.
Fisher's Exact Test
----------------------------------
Cell (1,1) Frequency (F) 129
Left-sided Pr <= F 0.1294
Right-sided Pr >= F 1.0000
Table Probability (P) 1.1294
Two-sided Pr <= P 0.2473
Estimates of the Relative Risk (Row1/Row2)
Type of Study Value 95% Confidence Limits
-----------------------------------------------------------------
Cohort (Col1 Risk) 0.9773 0.9522 1.0030
One or more risk estimates not computed --- zero cell.
Effective Sample Size = 260
Frequency Missing = 20
European-American DVT 14:33 Tuesday, June 18, 2002 25
SNP = CD14.1283
Allele Frequency
Frequency|
Percent |AA |GA | Total
---------+--------+--------+
Case | 63 | 3 | 66
| 48.46 | 2.31 | 50.77
---------+--------+--------+
Control | 64 | 0 | 64
| 49.23 | 0.00 | 49.23
---------+--------+--------+
Total 127 3 130
97.69 2.31 100.00
Frequency Missing = 10
Statistics for Table of Allele Frequency
Statistic DF Value Prob
------------------------------------------------------
Chi-Square 1 2.9778 0.0844
Likelihood Ratio Chi-Square 1 4.1360 0.0420
Continuity Adj. Chi-Square 1 1.3029 0.2537
Mantel-Haenszel Chi-Square 1 2.9549 0.0856
Phi Coefficient -0.1513
Contingency Coefficient 0.1496
Cramer's V -0.1513
WARNING: 50% of the cells have expected counts less than 5.
(Asymptotic) Chi-Square may not be a valid test.
Pearson Chi-Square Test
----------------------------------
Chi-Square 2.9778
DF 1
Asymptotic Pr > ChiSq 0.0844
Exact Pr >= ChiSq 0.2444
Fisher's Exact Test
----------------------------------
Cell (1,1) Frequency (F) 63
Left-sided Pr <= F 0.1279
Right-sided Pr >= F 1.0000
Table Probability (P) 1.1279
Two-sided Pr <= P 0.2444
Estimates of the Relative Risk (Row1/Row2)
Type of Study Value 95% Confidence Limits
-----------------------------------------------------------------
Cohort (Col1 Risk) 0.9545 0.9056 1.0061
One or more risk estimates not computed --- zero cell.
Effective Sample Size = 130
Frequency Missing = 10
European-American DVT 14:33 Tuesday, June 18, 2002 26
SNP = CD14.6080
Allele Frequency
Frequency|
Percent |A |G | Total
---------+--------+--------+
Case | 55 | 69 | 124
| 23.11 | 28.99 | 52.10
---------+--------+--------+
Control | 64 | 50 | 114
| 26.89 | 21.01 | 47.90
---------+--------+--------+
Total 119 119 238
50.00 50.00 100.00
Frequency Missing = 42
Statistics for Table of Allele Frequency
Statistic DF Value Prob
------------------------------------------------------
Chi-Square 1 3.2999 0.0693
Likelihood Ratio Chi-Square 1 3.3077 0.0690
Continuity Adj. Chi-Square 1 2.8454 0.0916
Mantel-Haenszel Chi-Square 1 3.2861 0.0699
Phi Coefficient -0.1178
Contingency Coefficient 0.1169
Cramer's V -0.1178
Fisher's Exact Test
----------------------------------
Cell (1,1) Frequency (F) 55
Left-sided Pr <= F 0.0457
Right-sided Pr >= F 0.9743
Table Probability (P) 0.0200
Two-sided Pr <= P 0.0914
Estimates of the Relative Risk (Row1/Row2)
Type of Study Value 95% Confidence Limits
-----------------------------------------------------------------
Case-Control (Odds Ratio) 0.6227 0.3731 1.0393
Cohort (Col1 Risk) 0.7901 0.6120 1.0199
Cohort (Col2 Risk) 1.2687 0.9778 1.6461
Effective Sample Size = 238
Frequency Missing = 42
WARNING: 15% of the data are missing.
European-American DVT 14:33 Tuesday, June 18, 2002 27
SNP = CD14.6080
Allele Frequency
Frequency|
Percent |AA |GA |GG | Total
---------+--------+--------+--------+
Case | 10 | 35 | 17 | 62
| 8.40 | 29.41 | 14.29 | 52.10
---------+--------+--------+--------+
Control | 17 | 30 | 10 | 57
| 14.29 | 25.21 | 8.40 | 47.90
---------+--------+--------+--------+
Total 27 65 27 119
22.69 54.62 22.69 100.00
Frequency Missing = 21
Statistics for Table of Allele Frequency
Statistic DF Value Prob
------------------------------------------------------
Chi-Square 2 3.8109 0.1488
Likelihood Ratio Chi-Square 2 3.8463 0.1461
Mantel-Haenszel Chi-Square 1 3.6055 0.0576
Phi Coefficient 0.1790
Contingency Coefficient 0.1762
Cramer's V 0.1790
Pearson Chi-Square Test
----------------------------------
Chi-Square 3.8109
DF 2
Asymptotic Pr > ChiSq 0.1488
Exact Pr >= ChiSq 0.1448
Effective Sample Size = 119
Frequency Missing = 21
WARNING: 15% of the data are missing.
European-American DVT 14:33 Tuesday, June 18, 2002 28
SNP = CD14.7066
Allele Frequency
Frequency|
Percent |C |T | Total
---------+--------+--------+
Case | 64 | 76 | 140
| 23.19 | 27.54 | 50.72
---------+--------+--------+
Control | 75 | 61 | 136
| 27.17 | 22.10 | 49.28
---------+--------+--------+
Total 139 137 276
50.36 49.64 100.00
Frequency Missing = 4
Statistics for Table of Allele Frequency
Statistic DF Value Prob
------------------------------------------------------
Chi-Square 1 2.4554 0.1171
Likelihood Ratio Chi-Square 1 2.4591 0.1168
Continuity Adj. Chi-Square 1 2.0925 0.1480
Mantel-Haenszel Chi-Square 1 2.4465 0.1178
Phi Coefficient -0.0943
Contingency Coefficient 0.0939
Cramer's V -0.0943
Fisher's Exact Test
----------------------------------
Cell (1,1) Frequency (F) 64
Left-sided Pr <= F 0.0739
Right-sided Pr >= F 0.9543
Table Probability (P) 0.0283
Two-sided Pr <= P 0.1200
Estimates of the Relative Risk (Row1/Row2)
Type of Study Value 95% Confidence Limits
-----------------------------------------------------------------
Case-Control (Odds Ratio) 0.6849 0.4263 1.1003
Cohort (Col1 Risk) 0.8290 0.6549 1.0493
Cohort (Col2 Risk) 1.2103 0.9516 1.5394
Effective Sample Size = 276
Frequency Missing = 4
European-American DVT 14:33 Tuesday, June 18, 2002 29
SNP = CD14.7066
Allele Frequency
Frequency|
Percent |CC |CT |TT | Total
---------+--------+--------+--------+
Case | 13 | 38 | 19 | 70
| 9.42 | 27.54 | 13.77 | 50.72
---------+--------+--------+--------+
Control | 21 | 33 | 14 | 68
| 15.22 | 23.91 | 10.14 | 49.28
---------+--------+--------+--------+
Total 34 71 33 138
24.64 51.45 23.91 100.00
Frequency Missing = 2
Statistics for Table of Allele Frequency
Statistic DF Value Prob
------------------------------------------------------
Chi-Square 2 2.9637 0.2272
Likelihood Ratio Chi-Square 2 2.9840 0.2249
Mantel-Haenszel Chi-Square 1 2.5105 0.1131
Phi Coefficient 0.1465
Contingency Coefficient 0.1450
Cramer's V 0.1465
Pearson Chi-Square Test
----------------------------------
Chi-Square 2.9637
DF 2
Asymptotic Pr > ChiSq 0.2272
Exact Pr >= ChiSq 0.2368
Effective Sample Size = 138
Frequency Missing = 2
African-American Asthma 14:33 Tuesday, June 18, 2002 30
SNP = CD14.1283
Allele Frequency
Frequency|
Percent |A |G | Total
---------+--------+--------+
Case | 145 | 9 | 154
| 41.19 | 2.56 | 43.75
---------+--------+--------+
Control | 184 | 14 | 198
| 52.27 | 3.98 | 56.25
---------+--------+--------+
Total 329 23 352
93.47 6.53 100.00
Frequency Missing = 12
Statistics for Table of Allele Frequency
Statistic DF Value Prob
------------------------------------------------------
Chi-Square 1 0.2134 0.6441
Likelihood Ratio Chi-Square 1 0.2153 0.6427
Continuity Adj. Chi-Square 1 0.0598 0.8068
Mantel-Haenszel Chi-Square 1 0.2128 0.6446
Phi Coefficient 0.0246
Contingency Coefficient 0.0246
Cramer's V 0.0246
Fisher's Exact Test
----------------------------------
Cell (1,1) Frequency (F) 145
Left-sided Pr <= F 0.7497
Right-sided Pr >= F 0.4066
Table Probability (P) 0.1564
Two-sided Pr <= P 0.6714
Estimates of the Relative Risk (Row1/Row2)
Type of Study Value 95% Confidence Limits
-----------------------------------------------------------------
Case-Control (Odds Ratio) 1.2258 0.5160 2.9120
Cohort (Col1 Risk) 1.0132 0.9590 1.0705
Cohort (Col2 Risk) 0.8265 0.3675 1.8589
Effective Sample Size = 352
Frequency Missing = 12
African-American Asthma 14:33 Tuesday, June 18, 2002 31
SNP = CD14.1283
Allele Frequency
Frequency|
Percent |AA |GA |GG | Total
---------+--------+--------+--------+
Case | 69 | 7 | 1 | 77
| 39.20 | 3.98 | 0.57 | 43.75
---------+--------+--------+--------+
Control | 85 | 14 | 0 | 99
| 48.30 | 7.95 | 0.00 | 56.25
---------+--------+--------+--------+
Total 154 21 1 176
87.50 11.93 0.57 100.00
Frequency Missing = 6
Statistics for Table of Allele Frequency
Statistic DF Value Prob
------------------------------------------------------
Chi-Square 2 2.2813 0.3196
Likelihood Ratio Chi-Square 2 2.6730 0.2628
Mantel-Haenszel Chi-Square 1 0.2074 0.6488
Phi Coefficient 0.1139
Contingency Coefficient 0.1131
Cramer's V 0.1139
WARNING: 33% of the cells have expected counts less than 5.
(Asymptotic) Chi-Square may not be a valid test.
Pearson Chi-Square Test
----------------------------------
Chi-Square 2.2813
DF 2
Asymptotic Pr > ChiSq 0.3196
Exact Pr >= ChiSq 0.2931
Effective Sample Size = 176
Frequency Missing = 6
African-American Asthma 14:33 Tuesday, June 18, 2002 32
SNP = CD14.6080
Allele Frequency
Frequency|
Percent |A |G | Total
---------+--------+--------+
Case | 85 | 67 | 152
| 24.57 | 19.36 | 43.93
---------+--------+--------+
Control | 126 | 68 | 194
| 36.42 | 19.65 | 56.07
---------+--------+--------+
Total 211 135 346
60.98 39.02 100.00
Frequency Missing = 18
Statistics for Table of Allele Frequency
Statistic DF Value Prob
------------------------------------------------------
Chi-Square 1 2.9190 0.0875
Likelihood Ratio Chi-Square 1 2.9143 0.0878
Continuity Adj. Chi-Square 1 2.5519 0.1102
Mantel-Haenszel Chi-Square 1 2.9105 0.0880
Phi Coefficient -0.0918
Contingency Coefficient 0.0915
Cramer's V -0.0918
Fisher's Exact Test
----------------------------------
Cell (1,1) Frequency (F) 85
Left-sided Pr <= F 0.0552
Right-sided Pr >= F 0.9655
Table Probability (P) 0.0207
Two-sided Pr <= P 0.0964
Estimates of the Relative Risk (Row1/Row2)
Type of Study Value 95% Confidence Limits
-----------------------------------------------------------------
Case-Control (Odds Ratio) 0.6847 0.4430 1.0581
Cohort (Col1 Risk) 0.8610 0.7228 1.0256
Cohort (Col2 Risk) 1.2575 0.9675 1.6346
Effective Sample Size = 346
Frequency Missing = 18
African-American Asthma 14:33 Tuesday, June 18, 2002 33
SNP = CD14.6080
Allele Frequency
Frequency|
Percent |AA |GA |GG | Total
---------+--------+--------+--------+
Case | 21 | 43 | 12 | 76
| 12.14 | 24.86 | 6.94 | 43.93
---------+--------+--------+--------+
Control | 41 | 44 | 12 | 97
| 23.70 | 25.43 | 6.94 | 56.07
---------+--------+--------+--------+
Total 62 87 24 173
35.84 50.29 13.87 100.00
Frequency Missing = 9
Statistics for Table of Allele Frequency
Statistic DF Value Prob
------------------------------------------------------
Chi-Square 2 3.9725 0.1372
Likelihood Ratio Chi-Square 2 4.0245 0.1337
Mantel-Haenszel Chi-Square 1 3.0768 0.0794
Phi Coefficient 0.1515
Contingency Coefficient 0.1498
Cramer's V 0.1515
Pearson Chi-Square Test
----------------------------------
Chi-Square 3.9725
DF 2
Asymptotic Pr > ChiSq 0.1372
Exact Pr >= ChiSq 0.1463
Effective Sample Size = 173
Frequency Missing = 9
African-American Asthma 14:33 Tuesday, June 18, 2002 34
SNP = CD14.7066
Allele Frequency
Frequency|
Percent |C |T | Total
---------+--------+--------+
Case | 90 | 62 | 152
| 25.42 | 17.51 | 42.94
---------+--------+--------+
Control | 130 | 72 | 202
| 36.72 | 20.34 | 57.06
---------+--------+--------+
Total 220 134 354
62.15 37.85 100.00
Frequency Missing = 10
Statistics for Table of Allele Frequency
Statistic DF Value Prob
------------------------------------------------------
Chi-Square 1 0.9763 0.3231
Likelihood Ratio Chi-Square 1 0.9745 0.3236
Continuity Adj. Chi-Square 1 0.7698 0.3803
Mantel-Haenszel Chi-Square 1 0.9736 0.3238
Phi Coefficient -0.0525
Contingency Coefficient 0.0524
Cramer's V -0.0525
Fisher's Exact Test
----------------------------------
Cell (1,1) Frequency (F) 90
Left-sided Pr <= F 0.1901
Right-sided Pr >= F 0.8640
Table Probability (P) 0.0541
Two-sided Pr <= P 0.3759
Estimates of the Relative Risk (Row1/Row2)
Type of Study Value 95% Confidence Limits
-----------------------------------------------------------------
Case-Control (Odds Ratio) 0.8040 0.5214 1.2397
Cohort (Col1 Risk) 0.9200 0.7784 1.0874
Cohort (Col2 Risk) 1.1444 0.8767 1.4938
Effective Sample Size = 354
Frequency Missing = 10
African-American Asthma 14:33 Tuesday, June 18, 2002 35
SNP = CD14.7066
Allele Frequency
Frequency|
Percent |CC |CT |TT | Total
---------+--------+--------+--------+
Case | 25 | 40 | 11 | 76
| 14.12 | 22.60 | 6.21 | 42.94
---------+--------+--------+--------+
Control | 43 | 44 | 14 | 101
| 24.29 | 24.86 | 7.91 | 57.06
---------+--------+--------+--------+
Total 68 84 25 177
38.42 47.46 14.12 100.00
Frequency Missing = 5
Statistics for Table of Allele Frequency
Statistic DF Value Prob
------------------------------------------------------
Chi-Square 2 1.8204 0.4024
Likelihood Ratio Chi-Square 2 1.8305 0.4004
Mantel-Haenszel Chi-Square 1 0.9793 0.3224
Phi Coefficient 0.1014
Contingency Coefficient 0.1009
Cramer's V 0.1014
Pearson Chi-Square Test
----------------------------------
Chi-Square 1.8204
DF 2
Asymptotic Pr > ChiSq 0.4024
Exact Pr >= ChiSq 0.4041
Effective Sample Size = 177
Frequency Missing = 5
|
