Innate Immunity in Heart, Lung and Blood Disease
Programs for Genomic Applications
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European-American Asthma 11:50 Wednesday, February 4, 2004 22
SNP = CCL26_5157
The FREQ Procedure
Table of Allele Frequency
Allele Frequency
Frequency|
Percent |C |T | Total
---------+--------+--------+
Control | 711 | 133 | 844
| 42.73 | 7.99 | 50.72
---------+--------+--------+
Case | 673 | 147 | 820
| 40.44 | 8.83 | 49.28
---------+--------+--------+
Total 1384 280 1664
83.17 16.83 100.00
Frequency Missing = 276
Statistics for Table of Allele Frequency
Statistic DF Value Prob
------------------------------------------------------
Chi-Square 1 1.3975 0.2371
Likelihood Ratio Chi-Square 1 1.3976 0.2371
Continuity Adj. Chi-Square 1 1.2468 0.2642
Mantel-Haenszel Chi-Square 1 1.3966 0.2373
Phi Coefficient 0.0290
Contingency Coefficient 0.0290
Cramer's V 0.0290
Fisher's Exact Test
----------------------------------
Cell (1,1) Frequency (F) 711
Left-sided Pr <= F 0.8939
Right-sided Pr >= F 0.1321
Table Probability (P) 0.0260
Two-sided Pr <= P 0.2390
Estimates of the Relative Risk (Row1/Row2)
Type of Study Value 95% Confidence Limits
-----------------------------------------------------------------
Case-Control (Odds Ratio) 1.1677 0.9029 1.5101
Cohort (Col1 Risk) 1.0264 0.9829 1.0718
Cohort (Col2 Risk) 0.8790 0.7097 1.0887
Effective Sample Size = 1664
Frequency Missing = 276
WARNING: 14% of the data are missing.
European-American Asthma 11:50 Wednesday, February 4, 2004 23
SNP = CCL26_5157
The FREQ Procedure
Table of Allele Frequency
Allele Frequency
Frequency|
Percent |2 |4 | Total
---------+--------+--------+
Control | 412 | 10 | 422
| 49.52 | 1.20 | 50.72
---------+--------+--------+
Case | 396 | 14 | 410
| 47.60 | 1.68 | 49.28
---------+--------+--------+
Total 808 24 832
97.12 2.88 100.00
Frequency Missing = 138
Statistics for Table of Allele Frequency
Statistic DF Value Prob
------------------------------------------------------
Chi-Square 1 0.8106 0.3679
Likelihood Ratio Chi-Square 1 0.8136 0.3671
Continuity Adj. Chi-Square 1 0.4805 0.4882
Mantel-Haenszel Chi-Square 1 0.8096 0.3682
Phi Coefficient 0.0312
Contingency Coefficient 0.0312
Cramer's V 0.0312
Pearson Chi-Square Test
----------------------------------
Chi-Square 0.8106
DF 1
Asymptotic Pr > ChiSq 0.3679
Exact Pr >= ChiSq 0.4120
Fisher's Exact Test
----------------------------------
Cell (1,1) Frequency (F) 412
Left-sided Pr <= F 0.8660
Right-sided Pr >= F 0.2444
Table Probability (P) 0.1104
Two-sided Pr <= P 0.4120
European-American Asthma 11:50 Wednesday, February 4, 2004 24
SNP = CCL26_5157
The FREQ Procedure
Statistics for Table of Allele Frequency
Estimates of the Relative Risk (Row1/Row2)
Type of Study Value 95% Confidence Limits
-----------------------------------------------------------------
Case-Control (Odds Ratio) 1.4566 0.6395 3.3175
Cohort (Col1 Risk) 1.0108 0.9873 1.0349
Cohort (Col2 Risk) 0.6940 0.3118 1.5445
Odds Ratio (Case-Control Study)
-----------------------------------
Odds Ratio 1.4566
Asymptotic Conf Limits
95% Lower Conf Limit 0.6395
95% Upper Conf Limit 3.3175
Exact Conf Limits
95% Lower Conf Limit 0.5935
95% Upper Conf Limit 3.7098
Effective Sample Size = 832
Frequency Missing = 138
WARNING: 14% of the data are missing.
European-American Asthma 11:50 Wednesday, February 4, 2004 25
SNP = CCL26_7853
The FREQ Procedure
Table of Allele Frequency
Allele Frequency
Frequency|
Percent |G |T | Total
---------+--------+--------+
Control | 478 | 206 | 684
| 32.21 | 13.88 | 46.09
---------+--------+--------+
Case | 586 | 214 | 800
| 39.49 | 14.42 | 53.91
---------+--------+--------+
Total 1064 420 1484
71.70 28.30 100.00
Frequency Missing = 456
Statistics for Table of Allele Frequency
Statistic DF Value Prob
------------------------------------------------------
Chi-Square 1 2.0600 0.1512
Likelihood Ratio Chi-Square 1 2.0571 0.1515
Continuity Adj. Chi-Square 1 1.8974 0.1684
Mantel-Haenszel Chi-Square 1 2.0586 0.1513
Phi Coefficient -0.0373
Contingency Coefficient 0.0372
Cramer's V -0.0373
Fisher's Exact Test
----------------------------------
Cell (1,1) Frequency (F) 478
Left-sided Pr <= F 0.0843
Right-sided Pr >= F 0.9322
Table Probability (P) 0.0165
Two-sided Pr <= P 0.1653
Estimates of the Relative Risk (Row1/Row2)
Type of Study Value 95% Confidence Limits
-----------------------------------------------------------------
Case-Control (Odds Ratio) 0.8474 0.6758 1.0625
Cohort (Col1 Risk) 0.9540 0.8943 1.0177
Cohort (Col2 Risk) 1.1259 0.9577 1.3236
Effective Sample Size = 1484
Frequency Missing = 456
WARNING: 24% of the data are missing.
European-American Asthma 11:50 Wednesday, February 4, 2004 26
SNP = CCL26_7853
The FREQ Procedure
Table of Allele Frequency
Allele Frequency
Frequency|
Percent |3 |4 | Total
---------+--------+--------+
Control | 175 | 167 | 342
| 23.58 | 22.51 | 46.09
---------+--------+--------+
Case | 211 | 189 | 400
| 28.44 | 25.47 | 53.91
---------+--------+--------+
Total 386 356 742
52.02 47.98 100.00
Frequency Missing = 228
Statistics for Table of Allele Frequency
Statistic DF Value Prob
------------------------------------------------------
Chi-Square 1 0.1845 0.6675
Likelihood Ratio Chi-Square 1 0.1845 0.6675
Continuity Adj. Chi-Square 1 0.1266 0.7220
Mantel-Haenszel Chi-Square 1 0.1842 0.6677
Phi Coefficient -0.0158
Contingency Coefficient 0.0158
Cramer's V -0.0158
Pearson Chi-Square Test
----------------------------------
Chi-Square 0.1845
DF 1
Asymptotic Pr > ChiSq 0.6675
Exact Pr >= ChiSq 0.7125
Fisher's Exact Test
----------------------------------
Cell (1,1) Frequency (F) 175
Left-sided Pr <= F 0.3610
Right-sided Pr >= F 0.6926
Table Probability (P) 0.0536
Two-sided Pr <= P 0.7125
European-American Asthma 11:50 Wednesday, February 4, 2004 27
SNP = CCL26_7853
The FREQ Procedure
Statistics for Table of Allele Frequency
Estimates of the Relative Risk (Row1/Row2)
Type of Study Value 95% Confidence Limits
-----------------------------------------------------------------
Case-Control (Odds Ratio) 0.9386 0.7031 1.2531
Cohort (Col1 Risk) 0.9700 0.8442 1.1147
Cohort (Col2 Risk) 1.0334 0.8895 1.2007
Odds Ratio (Case-Control Study)
-----------------------------------
Odds Ratio 0.9386
Asymptotic Conf Limits
95% Lower Conf Limit 0.7031
95% Upper Conf Limit 1.2531
Exact Conf Limits
95% Lower Conf Limit 0.6958
95% Upper Conf Limit 1.2664
Effective Sample Size = 742
Frequency Missing = 228
WARNING: 24% of the data are missing.